Prolactin stimulates activation of c-jun N-terminal kinase (JNK).

  title={Prolactin stimulates activation of c-jun N-terminal kinase (JNK).},
  author={Kathryn L Schwertfeger and Seija Hunter and Lynn E. Heasley and Valerie Levresse and Ronald P. Leon and James V Degregori and Steven M. Anderson},
  journal={Molecular endocrinology},
  volume={14 10},
In recent years the mitogen-activated protein (MAP) kinase family has expanded to include both c-jun N-terminal kinases (JNKs), and the p38/HOG1 family in addition to the extracellular regulated kinase (ERK) family. These kinases are activated by a variety of growth factors, as well as extra- and intracellular insults such as osmotic stress, UV light, and chemotherapeutic agents. Stimulation of the PRL-dependent Nb2 cell line with PRL results in the rapid activation of JNK as determined by the… CONTINUE READING


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