Prolactin responses to neuroleptics in normal and schizophrenic subjects.

@article{Gruen1978ProlactinRT,
  title={Prolactin responses to neuroleptics in normal and schizophrenic subjects.},
  author={P. Gruen and E. Sachar and G. Langer and N. Altman and M. Leifer and A. Frantz and F. Halpern},
  journal={Archives of general psychiatry},
  year={1978},
  volume={35 1},
  pages={
          108-16
        }
}
The prolactin response to neuroleptics can serve as an index of dopamine blockade in humans. Plasma prolactin increments to single doses of chlorpromazine, and prolactin decrements to single doses of levodopa, were similar in normal and schizophrenic subjects. Antischizophrenic drugs of all chemical classes stimulated prolactin release,while chemically related drugs and other psychotropic agents ineffective in schizophrenia did not. The prolactin response to neuroleptic therapy occurred in all… Expand
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