Prolactin-releasing peptide regulates the cardiovascular system via corticotrophin-releasing hormone.

@article{Yamada2009ProlactinreleasingPR,
  title={Prolactin-releasing peptide regulates the cardiovascular system via corticotrophin-releasing hormone.},
  author={Takahiro Yamada and Akikazu Mochiduki and Yuki Sugimoto and Yoko Suzuki and Keiichi Itoi and Kinji Inoue},
  journal={Journal of neuroendocrinology},
  year={2009},
  volume={21 6},
  pages={586-93}
}
Prolactin-releasing peptide (PrRP)-producing neurones are known to be localised mainly in the medulla oblongata and to act as a stress mediator in the central nervous system. In addition, central administration of PrRP elevates the arterial pressure and heart rate. However, the neuronal pathway of the cardiovascular effects of PrRP has not been revealed. In the present study, we demonstrate that PrRP-immunoreactive neurones projected to the locus coeruleus (LC) and the paraventricular nucleus… CONTINUE READING

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