Prolactin inhibition of pregnant mare's serum stimulated follicle development in the rat ovary.

@article{Larsen1990ProlactinIO,
  title={Prolactin inhibition of pregnant mare's serum stimulated follicle development in the rat ovary.},
  author={Jennifer Lynne Larsen and A Bhanu and William D. Odell},
  journal={Endocrine research},
  year={1990},
  volume={16 4},
  pages={449-59}
}
Prolactin (PRL) effects on the female reproductive system have been presumed to occur primarily at the hypothalamic-pituitary level. The following studies were designed to evaluate whether PRL can directly alter gonadotropin actions at the ovarian level. In the first experiment, 10 groups of 7 cycling adult female rats were given a daily dose of pregnant mare's serum (PMS: 25 IU) and either saline (SAL) or PRL (0.25, 0.8, 2.5, 8, or 25 micrograms) twice daily for 4 days. In the second… CONTINUE READING

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