Prolactin and sodium lactate-induced panic

  title={Prolactin and sodium lactate-induced panic},
  author={Eric Hollander and Michael R. Liebowitz and Barry Steven Cohen and Jack M. Gorman and Donald F. Klein},
  journal={Psychiatry Research},
Sodium lactate infusions reliably induce panic attacks in panic disorder patients but not in normal controls, but the mechanism underlying this response is unknown. We studied the plasma prolactin response to infusion of 0.5 molar sodium lactate in 38 patients with panic disorder or agoraphobia with panic attacks, and 16 normal controls. As expected, baseline plasma prolactin was significantly higher in female subjects than in male subjects. However, the males who experienced lactate-induced… CONTINUE READING


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