Prolactin: a new therapeutic target in peripartum cardiomyopathy.

  title={Prolactin: a new therapeutic target in peripartum cardiomyopathy.},
  author={Hatice Aylin Yamac and Insa Bultmann and Karen Sliwa and Denise Hilfiker-Kleiner},
  volume={96 17},
Peripartum/postpartum cardiomyopathy (PPCM) is a potentially life-threatening disease of uncertain aetiology in previously healthy women. Clinical and experimental data suggested inflammation, autoimmune processes, apoptosis and endothelial dysfunction as typical pathophysiological features of PPCM. Recent data discovered that unbalanced peri/postpartum oxidative stress linked to proteolytic cleavage of the nursing hormone prolactin into a potent anti-angiogenic, pro-apoptotic and pro… CONTINUE READING

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