Prokaryotic translation: the interactive pathway leading to initiation.

  title={Prokaryotic translation: the interactive pathway leading to initiation.},
  author={John G. McCarthy and Richard Brimacombe},
  journal={Trends in genetics : TIG},
  volume={10 11},
Finding answers to the many open questions concerning the mechanism and control of prokaryotic translation remains one of the central challenges of molecular biology. In fact, recent experimental data even force us to reconsider aspects that were previously thought to be established fact. Here, we attempt a synthesis of new and not-so-new information, which leads to a revised and testable working hypothesis for translational initiation.