Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes

@article{Truyen2005ProinsulinLA,
  title={Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes},
  author={Inge Truyen and Pieter Pauw and Peer Nobert J{\o}rgensen and Chris van Schravendijk and Onyedikachi Ubani and Katelijn Decochez and Evy Vandemeulebroucke and Ilse Weets and Ren Mao and Daniel G Pipeleers and Frans K. Gorus and The Belgian Diabetes Registry},
  journal={Diabetologia},
  year={2005},
  volume={48},
  pages={2322-2329}
}
Aims/hypothesisWe investigated whether random proinsulin levels and proinsulin:C-peptide ratio (PI:C) complement immune and genetic markers for identifying relatives at high risk of type 1 diabetes.Materials and methodsDuring an initial sampling, random glycaemia, proinsulin, PI:C and HLA DQ genotype were determined in 561 non-diabetic first-degree relatives who had been positive for islet autoantibodies on one or more occasions and in 561 age- and sex-matched persistently antibody-negative… CONTINUE READING
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Combination Immunotherapy for Type 1 Diabetes

  • Current diabetes reports
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 48 REFERENCES

Prediction of type 1 diabetes in first-degree relatives using a combination of insulin, glutamic acid decarboxylase and ICA 512 bdc/IA-2 autoantibodies

CF Verge, R Gianani, E Kawasaki
  • Diabetes
  • 1996
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Effects of insulin in relatives of patients with type 1 diabetes mellitus

K Decochez, IH DeLeeuw, B Keymeulen
  • N Engl J Med
  • 2002

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