Proinflammatory doses of diesel exhaust in healthy subjects fail to elicit equivalent or augmented airway inflammation in subjects with asthma.

@article{Behndig2011ProinflammatoryDO,
  title={Proinflammatory doses of diesel exhaust in healthy subjects fail to elicit equivalent or augmented airway inflammation in subjects with asthma.},
  author={Annelie F Behndig and Nirina Larsson and Joanna L Brown and Nikolai Stenfors and Ragnberth Helleday and Sean T. Duggan and Rosamund E. Dove and Susan J. Wilson and Thomas Sandstrom and F. J. Kelly and Ian S. Mudway and Anders Blomberg},
  journal={Thorax},
  year={2011},
  volume={66 1},
  pages={12-9}
}
BACKGROUND Exposure to traffic-derived air pollutants, particularly diesel emissions, has been associated with adverse health effects, predominantly in individuals with pre-existing respiratory disease. Here the hypothesis that this heightened sensitivity reflects an augmentation of the transient inflammatory response previously reported in healthy adults exposed to diesel exhaust is examined. METHODS 32 subjects with asthma (mild to moderate severity) and 23 healthy controls were exposed in… CONTINUE READING

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Airway inflammatory response to diesel exhaust generated at european transient cycle running conditions

J Pourazar, M Sehlstedt, AF Behndig
Am J Respir Crit Care Med • 2009

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