Proinflammatory cytokines such as IL-1 and tumor necrosis factor increase delta sleep

Objective: Alcoholics who are at risk for infectious disease show profound disturbances of sleep along with decrements of cellular immunity. This study examined the relationships between sleep, nocturnal expression of immunoregulatory cytokines, and natural killer (NK) cell activity in alcoholic patients as compared with control subjects. Methods: Alcoholic… CONTINUE READING