Proinflammatory cytokine production in liver regeneration is Myd88-dependent, but independent of Cd14, Tlr2, and Tlr4.

@article{Campbell2006ProinflammatoryCP,
  title={Proinflammatory cytokine production in liver regeneration is Myd88-dependent, but independent of Cd14, Tlr2, and Tlr4.},
  author={Jean S. Campbell and Kimberly J. Riehle and John T. Brooling and Renay L. Bauer and Claudia Mitchell and Nelson Fausto},
  journal={Journal of immunology},
  year={2006},
  volume={176 4},
  pages={2522-8}
}
TNF and IL-6 are considered to be important to the initiation or priming phase of liver regeneration. However, the signaling pathways that lead to the production of these cytokines after partial hepatectomy (PH) have not been identified. Enteric-derived LPS appears to be important to liver regeneration, possibly by stimulating proinflammatory cytokine production after surgery. To determine whether LPS signaling pathways are involved in the regulation of the proinflammatory cytokines TNF and IL… CONTINUE READING