Proinflammatory cytokine interleukin-6 in prostate carcinogenesis.

  • Zoran Culig
  • Published 2014 in
    American journal of clinical and experimental…

Abstract

Interleukin-6 (IL-6) is a multifunctional pro-inflammatory cytokine which is expressed in clinical specimens obtained from patients with prostate cancer and in multiple cell lines. IL-6 expression is regulated in prostate cancer by several oncogenes and tumor suppressors. IL-6 activates in prostate cancer pathways of Janus kinases/signal transducers and… (More)

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