Proinflammatory cytokine expression in the lung of pigs with porcine circovirus type 2-associated respiratory disease.

@article{Chae2011ProinflammatoryCE,
  title={Proinflammatory cytokine expression in the lung of pigs with porcine circovirus type 2-associated respiratory disease.},
  author={Joon-seok Chae and Kyoung-Seong Choi},
  journal={Research in veterinary science},
  year={2011},
  volume={90 2},
  pages={321-3}
}
Porcine circovirus type 2 (PCV2) causes a significant health problem for the swine industry worldwide. In this study, we investigated the cytokine expression profiles (IFN-γ, IL-1α, IL-8, and IL-10) in the lungs of pigs with PCV2-associated respiratory disease. The mRNA expressions of IL-1α and IL-8 were significantly up-regulated in pigs with PCV2-associated respiratory disease, while IL-10 expression was not detected. These results suggest that the increased expressions of proinflammatory… CONTINUE READING