Proinflammatory-activated trigeminal satellite cells promote neuronal sensitization: relevance for migraine pathology

@article{Capuano2009ProinflammatoryactivatedTS,
  title={Proinflammatory-activated trigeminal satellite cells promote neuronal sensitization: relevance for migraine pathology},
  author={Alessandro Capuano and Alice De Corato and Lucia Lisi and Giuseppe Tringali and Pierluigi Navarra and Cinzia Dello Russo},
  journal={Molecular Pain},
  year={2009},
  volume={5},
  pages={43 - 43}
}
BACKGROUND Migraine is a complex, chronic, painful, neurovascular disorder characterized by episodic activation of the trigeminal system. Increased levels of calcitonin gene-related peptide (CGRP) are found at different levels during migraine attacks. Interestingly, CGRP is also released within the trigeminal ganglia suggesting possible local effects on satellite cells, a specialized type of glia that ensheaths trigeminal neurons. CGRP was shown to enhance satellite-cell production of… CONTINUE READING
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