Proinflammatory Stimuli Engage Brahma Related Gene 1 and Brahma in Endothelial Injury

@article{Fang2013ProinflammatorySE,
  title={Proinflammatory Stimuli Engage Brahma Related Gene 1 and Brahma in Endothelial Injury},
  author={Fei Fang and Dewei Chen and Liming Yu and X. Dai and Yuyu Yang and W. Tian and X. Cheng and H. Xu and X. Weng and M. Fang and Jiliang Zhou and Yuqi Gao and Qi Chen and Yong Xu},
  journal={Circulation Research},
  year={2013},
  volume={113},
  pages={986–996}
}
Rationale: Endothelial dysfunction inflicted by inflammation is found in a host of cardiovascular pathologies. One hallmark event in this process is the aggregation and adhesion of leukocyte to the vessel wall mediated by the upregulation of adhesion molecules (CAM) in endothelial cells at the transcriptional level. The epigenetic modulator(s) of CAM transactivation and its underlying pathophysiological relevance remain poorly defined. Objective: Our goal was to determine the involvement of… Expand
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References

SHOWING 1-10 OF 54 REFERENCES
Endothelial-Dependent Mechanisms of Leukocyte Recruitment to the Vascular Wall
BRG1 increases transcription of proinflammatory genes in renal ischemia.
Sustained hypoxia promotes the development of a pulmonary artery-specific chronic inflammatory microenvironment.
Leucocyte/endothelium interactions and microvessel permeability: coupled or uncoupled?
  • P. He
  • Biology, Medicine
  • Cardiovascular research
  • 2010
...
1
2
3
4
5
...