Proinflammatory CD14+CD16+ monocytes are associated with vascular stiffness in predialysis patients with chronic kidney disease

@inproceedings{Lee2013ProinflammatoryCM,
  title={Proinflammatory CD14+CD16+ monocytes are associated with vascular stiffness in predialysis patients with chronic kidney disease},
  author={Jae-Won Lee and Eunjung Melanie Cho and Myung-Gyu Kim and Sang Kyung Jo and Wonyong Cho and Hyoung Kyu Kim},
  booktitle={Kidney research and clinical practice},
  year={2013}
}
BACKGROUND Chronic inflammation is frequently noted in patients with chronic kidney disease (CKD) and contributes to the development and progression of cardiovascular diseases. Monocytes are heterogeneous populations of cells, and they can be divided into subtypes with different phenotypes and functions based on CD14 and CD16 positivity. This study examined whether the proinflammatory CD14(+)CD16(+) monocyte subset expands in predialysis CKD patients, and also whether the expansion of these… CONTINUE READING