Progressive tissue injury in infantile hydrocephalus and prevention/reversal with shunt treatment.

@article{Jones2000ProgressiveTI,
  title={Progressive tissue injury in infantile hydrocephalus and prevention/reversal with shunt treatment.},
  author={Hazel C. Jones and N. G. Harris and James R. Rocca and R W Andersohn},
  journal={Neurological research},
  year={2000},
  volume={22 1},
  pages={89-96}
}
Infantile hydrocephalus, despite shunt treatment, can leave children with a variety of persistent neurological deficits. A rat strain (H-Tx) with inherited fetal-onset hydrocephalus, is a natural model for the study of progressive tissue changes resulting from hydrocephalus and the effects of shunt placement. The cerebral cortex of rat pups has been studied at post-natal day 4 (P4), early stage hydrocephalus and equivalent to a third trimester human fetus, at P11, intermediate stage… CONTINUE READING

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