Progressive systemic sclerosis associated with exposure to trichloroethylene.

  title={Progressive systemic sclerosis associated with exposure to trichloroethylene.},
  author={James E. Lockey and Curtis R Kelly and Grant W Cannon and Thomas Vail Colby and Virginia Aldrich and Gordon K. Livingston},
  journal={Journal of occupational medicine. : official publication of the Industrial Medical Association},
  volume={29 6},
Trichloroethylene (CHCL = CCL2) is a colorless aliphatic organic solvent with both historical use in medicine as an anesthetic agent and current use in industry as a degreasing agent. Although neither the etiology nor pathogenesis of progressive systemic sclerosis (scleroderma) has been established, this disease has been associated with a wide variety of seemingly unrelated compounds, including exposure to organic solvents. The authors describe a 47-year-old woman with previous excellent health… CONTINUE READING


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