Progressive symmetrical erythrokeratoderma: report of a Turkish family and evaluation for loricrin and connexin gene mutations.

@article{Akman2008ProgressiveSE,
  title={Progressive symmetrical erythrokeratoderma: report of a Turkish family and evaluation for loricrin and connexin gene mutations.},
  author={A. {\"U}nal Akman and Maureen Mass{\'e} and Ercan Mihçi and Gabriele Richard and Angela M. Christiano and Borja Balle and Mehmet Akif Çiftçioğlu and Erkan Alpsoy},
  journal={Clinical and experimental dermatology},
  year={2008},
  volume={33 5},
  pages={582-4}
}
We report here the first Turkish patient with progressive symmetric erythrokeratoderma. The patient's skin lesions appeared in the axillae at 3 months of age, and gradually spread to other flexural areas and to the trunk. Dermatological examination of the boy at 3.5 years of age revealed symmetric, hyperkeratotic plaques with erythematous outlines on the neck, wrists, armpits, trunk and posterior knees. The histopathological changes were nonspecific, including marked hyperkeratosis, irregular… CONTINUE READING

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