Progressive supranuclear palsy (PSP): a quantitative study of the pathological changes in cortical and subcortical regions of eight cases

@article{Armstrong2007ProgressiveSP,
  title={Progressive supranuclear palsy (PSP): a quantitative study of the pathological changes in cortical and subcortical regions of eight cases},
  author={Richard A Armstrong and Peter L. Lantos and Nigel J. Cairns},
  journal={Journal of Neural Transmission},
  year={2007},
  volume={114},
  pages={1569-1577}
}
In eight cases of progressive supranuclear palsy (PSP), neurofibrillary tangles (NFT) were numerous in the substantia nigra (SN), red nucleus (RN), locus caeruleus (LC), pontine nuclei (PN), and inferior olivary nucleus (ION) and abnormally enlarged neurons (EN) in the ION, LC and PN. Loss of Purkinje cells was evident in the cerebellum. Tufted astrocytes (TA) were abundant in the striatum, SN and RN and glial inclusions (‘coiled bodies’) (GI) in the midbrain (SN, RN) and pons (LC). Neuritic… CONTINUE READING

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