Progressive oculo-orofacial-speech apraxia (POOSA).

  title={Progressive oculo-orofacial-speech apraxia (POOSA).},
  author={Heidi L. Roth and Thomas A. Eskin and Diane Kendall and Kenneth M Heilman},
  volume={12 4},
A loss of speech can be related to disorders of the motor units (paresis), language deficits (aphasia), or speech programming deficits (apraxia of speech). Although apraxia of speech has been reported to be associated with degenerative diseases, we observed a patient with a unique constellation of signs that included apraxia of speech, oculo-orofacial apraxia and a supranuclear ophthalmoplegia in the absence of extrapyramidal (Parkinsonian) signs. Post-mortem examination revealed a loss of… CONTINUE READING