Progressive myoclonic epilepsies: a review of genetic and therapeutic aspects.

@article{Shahwan2005ProgressiveME,
  title={Progressive myoclonic epilepsies: a review of genetic and therapeutic aspects.},
  author={Amre Shahwan and Michael Farrell and Norman Delanty},
  journal={The Lancet. Neurology},
  year={2005},
  volume={4 4},
  pages={239-48}
}
The progressive myoclonic epilepsies (PMEs) are a group of symptomatic generalised epilepsies caused by rare disorders, most of which have a genetic component, a debilitating course, and a poor outcome. Challenges with PME arise from difficulty with diagnosis, especially in the early stages of the illness, and further problems of management and drug treatment. Recent advances in molecular genetics have helped achieve better understanding of the different disorders that cause PME. We review the… CONTINUE READING