Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy

Abstract

Duchenne muscular dystrophy (DMD) is caused by genetic deficiency of dystrophin and characterized by massive structural and functional changes of skeletal muscle tissue, leading to terminal muscle failure. We recently generated a novel genetically engineered pig model reflecting pathological hallmarks of human DMD better than the widely used mdx mouse. To… (More)
DOI: 10.1038/srep33362

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Cite this paper

@inproceedings{Froehlich2016ProgressiveMP, title={Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy}, author={Thomas Froehlich and Elisabeth Kemter and Florian Flenkenthaler and Nikolai Klymiuk and Kathrin A Otte and Andreas Blutke and Sabine Krause and Maggie C. Walter and Ruediger Wanke and Eckhard Wolf and Georg J. Arnold}, booktitle={Scientific reports}, year={2016} }