Progressive multiple sclerosis: pathology and pathogenesis

@article{Lassmann2012ProgressiveMS,
  title={Progressive multiple sclerosis: pathology and pathogenesis},
  author={H. Lassmann and J. Horssen and D. Mahad},
  journal={Nature Reviews Neurology},
  year={2012},
  volume={8},
  pages={647-656}
}
Major progress has been made during the past three decades in understanding the inflammatory process and pathogenetic mechanisms in multiple sclerosis (MS). Consequently, effective anti-inflammatory and immunomodulatory treatments are now available for patients in the relapsing–remitting stage of the disease. This Review summarizes studies on the pathology of progressive MS and discusses new data on the mechanisms underlying its pathogenesis. In progressive MS, as in relapsing–remitting MS… Expand
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