Progressive multifocal leukoencephalopathy : new concepts Leucoencefalopatia multifocal progressiva : novos conceitos

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the CNS caused by reactivation of JC virus ( JCV). Primary infection occurs in childhood and it is asymptomatic in most patients. Thereafter, the virus remains latent in the kidney, bone marrow and lymphoid organs, but, in a setting of cellular immunosuppression, the virus… (More)

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