Progressive multifocal leukoencephalopathy: improved survival of human immunodeficiency virus-infected patients in the protease inhibitor era.

@article{Dworkin1999ProgressiveML,
  title={Progressive multifocal leukoencephalopathy: improved survival of human immunodeficiency virus-infected patients in the protease inhibitor era.},
  author={Mark S. Dworkin and Peggy C Wan and Debra L. Hanson and Jeffrey L. Jones},
  journal={The Journal of infectious diseases},
  year={1999},
  volume={180 3},
  pages={621-5}
}
To examine factors affecting survival after diagnosis of progressive multifocal leukoencephalopathy (PML), we analyzed data from an observational cohort study, the Adult and Adolescent Spectrum of HIV Disease project. We identified 415 patients diagnosed with PML during 1990-1997. The median survival time after diagnosis was 1 month. By use of an extended proportional hazards, multivariate regression model, risk factors associated with decreased survival time included CD4 count <0.20 x 10(9… CONTINUE READING

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