Progressive multifocal leucoencephalopathy in a patient with idiopathic CD4+ lymphocytopenia.

@article{Moloney2012ProgressiveML,
  title={Progressive multifocal leucoencephalopathy in a patient with idiopathic CD4+ lymphocytopenia.},
  author={Fiachra Moloney and David A Gonz{\'a}lez Fern{\'a}ndez and H James Harrington},
  journal={Irish medical journal},
  year={2012},
  volume={105 3},
  pages={84-5}
}
Progressive multifocal leucoencephalopathy (PML) is an opportunistic, demyelinating neurological disease caused by reactivation of the JC polyomavirus. PML occurs almost exclusively in immunosuppressed individuals, with only isolated case reports of PML occurring in patients without apparent immunosuppression. Idiopathic CD4+ lymohocytopenia (ICL) is a syndrome defined by the Centre for Disease Control and Prevention as a CD4+ count <300 cells/uL or <20% of total T cell count on >1 occasion… CONTINUE READING