Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development.

Abstract

The 3' untranslated regions (3' UTRs) of mRNAs contain cis-acting elements for posttranscriptional regulation of gene expression. Here, we report that mouse genes tend to express mRNAs with longer 3' UTRs as embryonic development progresses. This global regulation is controlled by alternative polyadenylation and coordinates with initiation of organogenesis… (More)
DOI: 10.1073/pnas.0900028106

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Cite this paper

@article{Ji2009ProgressiveLO, title={Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development.}, author={Zhe Ji and Ju Youn Lee and Zhenhua Pan and Bingjun Jiang and Bin Tian}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2009}, volume={106 17}, pages={7028-33} }