Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study

@article{Howes2011ProgressiveII,
  title={Progressive increase in striatal dopamine synthesis capacity as patients develop psychosis: a PET study},
  author={O Howes and Smirti Bose and Federico E. Turkheimer and Isabel Valli and Alice Egerton and Daniel Stahl and Lucia R Valmaggia and Paul Allen and Robin Murray and Philip Mcguire},
  journal={Molecular Psychiatry},
  year={2011},
  volume={16},
  pages={885-886}
}
Converging in vivo evidence from neuroimaging studies indicates that psychotic disorders are associated with dysregulated striatal dopaminergic function, but whether the latter leads to the de novo onset of psychosis remains unclear (see reviews). We investigated this by using positron emission tomography to measure the longitudinal change in presynaptic… CONTINUE READING