Progressive impairment in motor skill learning at 12 and 20 weeks post 6-OHDA- SNc lesion in rats.

Abstract

Deficiency in skilled motor activity is primarily attributed to the loss of dopaminergic neurons in the pars compacta of substantia nigra (SNc), which can be detected by performance of the rotarod test. Previous reports have demonstrated impaired skilled motor behavior in rats during the pre-motor stage of Parkinson's disease (PD) (3-8 weeks post 6-OHDA… (More)
DOI: 10.1016/j.parkreldis.2010.12.017

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Cite this paper

@article{Gambhir2011ProgressiveII, title={Progressive impairment in motor skill learning at 12 and 20 weeks post 6-OHDA- SNc lesion in rats.}, author={Hardeep S Gambhir and Rashmi Mohan Mathur and Madhuri Behari}, journal={Parkinsonism & related disorders}, year={2011}, volume={17 6}, pages={476-8} }