Progressive hyperglycemia across the glucose tolerance continuum in older obese adults is related to skeletal muscle capillarization and nitric oxide bioavailability.

@article{Solomon2011ProgressiveHA,
  title={Progressive hyperglycemia across the glucose tolerance continuum in older obese adults is related to skeletal muscle capillarization and nitric oxide bioavailability.},
  author={Thomas P J Solomon and Jacob M Haus and Yanjun Li and John P Kirwan},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2011},
  volume={96 5},
  pages={1377-84}
}
CONTEXT Reduced tissue nutrient exposure may aid in the progression of glucose intolerance. OBJECTIVE The aim of the study was to examine peripheral tissue glucose disposal in relation to muscle capillarization and plasma nitric oxide bioavailability. DESIGN Participants were carefully matched for age, adiposity, and lipid status and stratified into normal (n = 20), impaired (n = 20), and type 2 diabetic (n = 20) glucose-tolerant groups. SETTING The study was conducted in an outpatient… CONTINUE READING

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