Progressive hemispheric shrinking in hemimegalencephaly: a possible role for seizure-related neuronal loss.

Abstract

Hemimegalencephaly (HME) is a developmental brain lesion consisting of a unilateral enlarged, dysplastic, and often highly epileptogenic cerebral hemisphere. Most patients exhibit early onset intractable seizures, status epilepticus, hemiplegia, hemianopsia, and developmental delay. Major surgical procedures are advocated for limiting the devastating… (More)
DOI: 10.1111/j.1469-8749.2008.03003.x

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