Progressive gray matter damage in patients with relapsing-remitting multiple sclerosis: a longitudinal diffusion tensor magnetic resonance imaging study.

@article{OrejaGuevara2005ProgressiveGM,
  title={Progressive gray matter damage in patients with relapsing-remitting multiple sclerosis: a longitudinal diffusion tensor magnetic resonance imaging study.},
  author={Celia Oreja-Guevara and Marco Rovaris and Giuseppe Iannucci and Paola Valsasina and Domenico Caputo and Rosella Cavarretta and Maria Pia Sormani and Pasquale Ferrante and Giancarlo Comi and Massimo Filippi},
  journal={Archives of neurology},
  year={2005},
  volume={62 4},
  pages={578-84}
}
BACKGROUND Diffusion tensor magnetic resonance imaging (DT MRI) has the potential to provide in vivo information about tissue microstructure. In multiple sclerosis (MS), DT MRI has disclosed the presence of occult structural damage in the normal-appearing brain tissues. OBJECTIVE To investigate whether DT MRI is sensitive to longitudinal changes of brain… CONTINUE READING