Progressive glomerulopathy with unusual deposits of striated structures: a new disease entity?

@article{Ohtani2010ProgressiveGW,
  title={Progressive glomerulopathy with unusual deposits of striated structures: a new disease entity?},
  author={Hiroshi Ohtani and Hideki Wakui and Atsushi Komatsuda and Hiroyuki Goto and Mitsunori Tada and Masatoyo Ozawa and Ryoji Kobayashi and Ken-ichi Sawada},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2010},
  volume={25 6},
  pages={2016-9}
}
A 68-year-old man developed proteinuria and renal insufficiency. A renal biopsy showed mesangial proliferation and double contour in almost all glomeruli. Congo red staining for amyloid was negative. Immunofluorescence microscopy revealed no deposition of immunoglobulins. Electron microscopy showed unusual deposits of striated structures mainly in the subendothelial space and the mesangium. These deposits contained regularly stacked straight electron-dense bands. Microfilament-like deposits… CONTINUE READING

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