Progressive genome-wide introgression in agricultural Campylobacter coli

@inproceedings{Sheppard2013ProgressiveGI,
  title={Progressive genome-wide introgression in agricultural Campylobacter coli},
  author={Samuel K. Sheppard and Xavier Didelot and Keith A. Jolley and Aaron E. Darling and Ben Pascoe and Guillaume M{\'e}ric and David J. Kelly and Alison J. Cody and Frances M. Colles and Norval J. C. Strachan and Iain D. Ogden and Ken Forbes and Nigel P French and Philip S. Carter and William Galbraith Miller and Noel Denis McCarthy and Robert R. Owen and Eva Litrup and Michael Wayland Egholm and Jason P. Affourtit and Stephen D. Bentley and Julian Parkhill and Martin C. J. Maiden and Daniel Falush},
  booktitle={Molecular ecology},
  year={2013}
}
Hybridization between distantly related organisms can facilitate rapid adaptation to novel environments, but is potentially constrained by epistatic fitness interactions among cell components. The zoonotic pathogens Campylobacter coli and C. jejuni differ from each other by around 15% at the nucleotide level, corresponding to an average of nearly 40 amino acids per protein-coding gene. Using whole genome sequencing, we show that a single C. coli lineage, which has successfully colonized an… CONTINUE READING

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