Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric

@article{Schlamp2006ProgressiveGC,
  title={Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric},
  author={Cassandra L. Schlamp and Yan Li and Joel A. Dietz and Katherine T Janssen and Robert W Nickells},
  journal={BMC Neuroscience},
  year={2006},
  volume={7},
  pages={66 - 66}
}
Glaucoma is a chronic neurodegenerative disease of the retina, characterized by the degeneration of axons in the optic nerve and retinal ganglion cell apoptosis. DBA/2J inbred mice develop chronic hereditary glaucoma and are an important model system to study the molecular mechanisms underlying this disease and novel therapeutic interventions designed to… CONTINUE READING