Progressive familial intrahepatic cholestasis: a personal perspective.

  • A. S. Knisely
  • Published 2000 in
    Pediatric and developmental pathology : the…


Progressive familial intrahepatic cholestasis (PFIC), originally described as "Byler disease" in an Amish kindred, has been distinguished from other forms of cholestatic liver disease in childhood by clinical findings, clinical-laboratory observations, and morphologic studies in biopsy, hepatectomy, and autopsy specimens. Correlation with genetic analyses… (More)


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