Progressive deformation of deep brain nuclei and hippocampal-amygdala formation in schizophrenia.

@article{Wang2008ProgressiveDO,
  title={Progressive deformation of deep brain nuclei and hippocampal-amygdala formation in schizophrenia.},
  author={Lei Wang and Daniel Mamah and Michael P. Harms and Meghana Karnik and Joseph L. Price and Mokhtar H. Gado and Paul A. Thompson and Deanna M. Barch and Michael I. Miller and John G. Csernansky},
  journal={Biological psychiatry},
  year={2008},
  volume={64 12},
  pages={1060-8}
}
BACKGROUND Progressive decreases in cortical gray matter volume have been reported in schizophrenia. However, studies of progressive change in deep brain nuclei and hippocampal-amygdala formation have not yielded consistent findings. METHODS Two high-resolution, T1-weighted magnetic resonance images were collected 2 years apart in 56 schizophrenia and 62 control subjects. Large-deformation high-dimensional brain mapping was used to generate surfaces for deep brain nuclei and hippocampal… CONTINUE READING
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