Progressive decrease in tissue glycogen content in rats with long-term cholestasis.

@article{Krahenbuhl1996ProgressiveDI,
  title={Progressive decrease in tissue glycogen content in rats with long-term cholestasis.},
  author={L Krahenbuhl and C. Talos and Juerg Reichen and Stephan Kraehenbuhl},
  journal={Hepatology},
  year={1996},
  volume={24 4},
  pages={902-7}
}
Liver and skeletal muscle glycogen metabolism were investigated in rats 1 and 4 weeks after bile duct ligation (BDL) and in pair-fed, sham-operated control rats. Livers were subjected to morphometric analysis to express glycogen content and enzyme activities per mL hepatocytes. One week after BDL, the hepatic glycogen content was 28.8 +/- 13.8 versus 38.6 +/- 16.4 mg/mL hepatocyte in BDL and control rats, respectively. Total activity of glycogen synthase (50.2 +/- 7.0 vs. 63.5 +/- 9.4 mU/mL… CONTINUE READING
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