Progressive changes in cortical metabolites at three stages of infantile hydrocephalus studied by in vitro NMR spectroscopy.

@article{Jones1997ProgressiveCI,
  title={Progressive changes in cortical metabolites at three stages of infantile hydrocephalus studied by in vitro NMR spectroscopy.},
  author={Hazel C. Jones and N. G. Harris and James R. Rocca and R W Andersohn},
  journal={Journal of neurotrauma},
  year={1997},
  volume={14 9},
  pages={587-602}
}
Infantile hydrocephalus is most often caused by an obstruction in the cerebrospinal fluid flow pathway and results in ventricular dilatation and chronic trauma to the surrounding brain. Surgical treatment alleviates the condition but does not cure or prevent neurological deficits. The H-Tx rat has severe hydrocephalus due to a spontaneous aqueduct obstruction in late gestation. In order to determine how hydrocephalus affects brain metabolism in tissue adjacent to the expanded ventricles… CONTINUE READING

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