Progressive cerebral atrophy in neuromyelitis optica.

@article{Warabi2015ProgressiveCA,
  title={Progressive cerebral atrophy in neuromyelitis optica.},
  author={Yoko Warabi and Toshiyuki Takahashi and Eiji Isozaki},
  journal={Multiple sclerosis},
  year={2015},
  volume={21 14},
  pages={
          1872-5
        }
}
We report two cases of neuromyelitis optica patients with progressive cerebral atrophy. The patients exhibited characteristic clinical features, including elderly onset, secondary progressive tetraparesis and cognitive impairment, abnormally elevated CSF protein and myelin basic protein levels, and extremely highly elevated serum anti-AQP-4 antibody titer. Because neuromyelitis optica pathology cannot switch from an inflammatory phase to the degenerative phase until the terminal phase… CONTINUE READING
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