Progressive caloric restriction induces dose-dependent changes in myocardial triglyceride content and diastolic function in healthy men.

@article{Hammer2008ProgressiveCR,
  title={Progressive caloric restriction induces dose-dependent changes in myocardial triglyceride content and diastolic function in healthy men.},
  author={Sebastiaan Hammer and Riet van der Meer and Hildo J. Lamb and Michael Sch{\"a}r and Albert de Roos and Jan Smit and Johannes Anthonius Romijn},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2008},
  volume={93 2},
  pages={497-503}
}
CONTEXT In animal experiments, high plasma concentrations of free fatty acids (FFAs) are associated with increased triglyceride (TG) stores in liver and heart, and impaired cardiac function. In humans caloric restriction increases plasma FFA levels. OBJECTIVE Our objective was to assess the effects of progressive caloric restriction on myocardial and hepatic TG content and myocardial function. DESIGN This was a prospective intervention study. PARTICIPANTS This study included 10 lean… CONTINUE READING

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