Progressive aphasia presenting with deep dyslexia and dysgraphia

  title={Progressive aphasia presenting with deep dyslexia and dysgraphia},
  author={Julie S. Snowden and J Kindell and Jennifer C. Thompson and Anna M. T. Richardson and David Neary},

Language training for oral and written naming impairment in primary progressive aphasia: a review

Overall, language training is able to induce immediate improvements of naming abilities in all variants of PPA and one factor that determines the choice of a particular approach is the compromised components of the lexical/semantic processing system.

Dysgraphia in primary progressive aphasia: Characterisation of impairments and therapy options

Background: Spelling impairment is common in primary progressive aphasia (PPA). Although behavioural interventions tend to focus on spoken language, remediation of written language may be desirable,

Primary progressive aphasia: a clinical approach

A clinical approach to the progressive aphasias is presented, based on the experience of these disorders and directed at non-specialists, and a prospect for future progress is concluded, emphasising generic information processing deficits and novel pathophysiological biomarkers.

Language impairment in primary progressive aphasia and other neurodegenerative diseases

The relationship between PPA and NDDs like Alzheimer's, Parkinson’s and Dyslexia is unraveled and an exhaustive approach towards the treatment of PPA is offered by combining the existing language therapies with clinical and pharmacological interventions.

Sensitivity of Speech Output to Delayed Auditory Feedback in Primary Progressive Aphasias

This work suggests that DAF may be an informative probe of pathophysiological mechanisms underpinning primary progressive aphasia: identification of “DAF responders” may open up an avenue to novel therapeutic applications.

Dysfunctional visual word form processing in progressive alexia.

The results suggest that progressive alexia is associated with a dysfunctional visual word form system, with or without substantial cortical atrophy, and demonstrate that functional MRI has the potential to reveal the neural bases of cognitive deficits in neurodegenerative patients at very early stages.

Mechanisms of auditory signal decoding in the progressive aphasias

The primary progressive aphasias (PPA) are a diverse group of neurodegenerative disorders that selectively target brain networks mediating language. The pathophysiology of PPA remains poorly

Understanding the neurobiological basis of reading disorders in aphasia and predicting patients' responses to reading therapy

It is demonstrated for the first time, that lesion-site is determinant in patients’ response to therapy and also that therapy response in new patients is predictable.

Nonpharmacological interventions for cognitive impairments following primary progressive aphasia: a systematic review of the literature

Results of the present review allows for recommendation of some nonpharmacological interventions for cognitive deficits following PPA as Practice Options.



Deep Dysphasic Performance in Non-fluent Progressive Aphasia: a Case Study

It is found that a patient (PW) with non-fluent progressive aphasia was impaired on a variety of verbal tasks that demand access to phonological representations and made semantic paraphasias and that her performance was influenced by imageability and lexical status.

Primary Progressive Aphasia: A Review

It is concluded that there is sufficiently consistent and converging evidence from clinical and imaging studies to support the claim that PNFA and SD are distinct subgroups of PPA, but there does not appear to be sufficient evidence at this point to support further discrimination within these progressive aphasic subgroups.

An Overview on Primary Progressive Aphasia and Its Variants

The neuropsychological data demonstrated that SD patients show the most characteristic pattern of impairment, while PNFA and LPA overlap within many cognitive domains, and the neuroimaging analysis showed left perisylvian region involvement.

Deep dysphasia: Further evidence on the relationship between phonological short-term memory and language processing impairments

A cognitive investigation of a case of deep dysphasia appearing in the context of primary progressive aphasia revealed difficulties in phoneme identification and rhyme judgement, in detecting grammatical class for orally presented words, and in oral and written naming.

Progressive Anomia with Preserved Oral Spelling and Automatic Speech

It is argued that automatic tasks provide phonological cues that facilitate phonological activation, and finds that phonological cueing of picture names has yielded superior naming than word reading and even repetition, a finding consistent with the notion that task characteristics influence likelihood of phonologicalactivation and naming success.

Modality-Specific Deterioration in Naming Verbs in Nonfluent Primary Progressive Aphasia

The results provide a new source of evidence for the hypothesis that there are distinct neural mechanisms for accessing lexical representations of nouns and verbs in language production and rule out a semantic locus for the grammatical class effects.

Cognition and anatomy in three variants of primary progressive aphasia

Cognitive, genetic, and anatomical features indicate that different PPA clinical variants may correspond to different underlying pathological processes.

Primary progressive aphasia: clinicopathological correlations

  • M. Grossman
  • Psychology, Medicine
    Nature Reviews Neurology
  • 2010
Clinopathological correlations in PPA suggest an association between a specific PPA variant and an underlying pathology, although many cases of PPA are associated with an unexpected pathology.