Progressive alterations in lipid and glucose metabolism during short-term fasting in young adult men.

@article{Klein1993ProgressiveAI,
  title={Progressive alterations in lipid and glucose metabolism during short-term fasting in young adult men.},
  author={Samuel Klein and Yoichi Sakurai and Johannes Anthonius Romijn and Robert M. Carroll},
  journal={The American journal of physiology},
  year={1993},
  volume={265 5 Pt 1},
  pages={E801-6}
}
Stable isotope tracers and indirect calorimetry were used to evaluate the progressive alterations in lipid and glucose metabolism after 12, 18, 24, 30, 42, 54, and 72 h of fasting in six healthy male volunteers. The rates of appearance (Ra) of glycerol and palmitic acid in plasma doubled from 2.08 +/- 0.22 and 1.63 +/- 0.20 mumol.kg-1 x min-1, respectively, after 12 h to 4.36 +/- 0.36 and 3.26 +/- 0.40 mumol.kg-1 x min-1, respectively, after 72 h of fasting (P < 0.01). Of the total increase in… CONTINUE READING