Progressive alcohol-induced sperm alterations leading to spermatogenic arrest, which was reversed after alcohol withdrawal.

@article{Sermondade2010ProgressiveAS,
  title={Progressive alcohol-induced sperm alterations leading to spermatogenic arrest, which was reversed after alcohol withdrawal.},
  author={Nathalie Sermondade and Han{\`e}ne Elloumi and Isabelle Berthaut and E. Emmanuelle Mathieu and Vanina Delarouzi{\`e}re and C{\'e}lia Ravel and Jacqueline Mandelbaum},
  journal={Reproductive biomedicine online},
  year={2010},
  volume={20 3},
  pages={324-7}
}
This is a report of a 6-year follow-up of a male patient's semen parameters during heavy chronic alcohol intoxication and after withdrawal. A slowly progressive negative impact of alcohol could be observed: isolated moderate teratozoospermia was firstly noted followed by oligoasthenoteratospermia. Then a severe worsening resulted in cryptozoospermia and ultimately in azoospermia. At this moment, the histological analysis of a testicular biopsy revealed a maturation arrest of the germinal cells… CONTINUE READING