Progressive Nonfluent Aphasia: Language, Cognitive, and PET Measures Contrasted with Probable Alzheimer's Disease

@article{Grossman1996ProgressiveNA,
  title={Progressive Nonfluent Aphasia: Language, Cognitive, and PET Measures Contrasted with Probable Alzheimer's Disease},
  author={Murray Grossman and Jenifer Mickanin and Kris Onishi and Elizabeth Hughes and Mark D'Esposito and Xin-Sheng Ding and Abass Alavi and Martin Reivich},
  journal={Journal of Cognitive Neuroscience},
  year={1996},
  volume={8},
  pages={135-154}
}
The purpose of this study was to compare the language and cognitive profiles of four progressive nonfluent aphasia (PNFA) patients with 25 probable Alzheimer's disease (pAD) patients, and to identify the distinct cortical defects associated with cognitive deficits in PNFA using positron emission tomography (PET). Longitudinal observations of PNFA patients revealed progressively telegraphic speech and writing and a gradual deterioration of sentence comprehension, but memory and visual… CONTINUE READING
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