Progressive Effects of N-myc Deficiency on Proliferation, Neurogenesis, and Morphogenesis in the Olfactory Epithelium

@inproceedings{Wittmann2014ProgressiveEO,
  title={Progressive Effects of N-myc Deficiency on Proliferation,
Neurogenesis, and Morphogenesis in the Olfactory Epithelium},
  author={Walter Wittmann and Thomas Schimmang and Lena Gunhaga},
  booktitle={Developmental neurobiology},
  year={2014}
}
N-myc belongs to the myc proto-oncogene family, which is involved in numerous cellular processes such as proliferation, growth, apoptosis, and differentiation. Conditional deletion of N-myc in the mouse nervous system disrupted brain development, indicating that N-myc plays an essential role during neural development. How the development of the olfactory epithelium and neurogenesis within are affected by the loss of N-myc has, however, not been determined. To address these issues, we examined… CONTINUE READING