Progression of tremor in early stages of Parkinson’s disease: a clinical and neuroimaging study

  title={Progression of tremor in early stages of Parkinson’s disease: a clinical and neuroimaging study},
  author={Jacopo Pasquini and Roberto Ceravolo and Zahi Qamhawi and Jee-Young Lee and G{\"u}nther Deuschl and David J. Brooks and Ubaldo Bonuccelli and Nicola Pavese},
Rest tremor is one of the cardinal signs of Parkinson's disease. Kinetic and postural tremors may also occur. The coexistence of these three types of tremor at disease onset and their subsequent progression could have important clinical and therapeutic implications but remain to be fully elucidated. We aimed to: (i) evaluate prevalence and progression of these three types of tremor in early stages of the disease; and (ii) investigate longitudinally the relationship between dopaminergic and… 

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