Progression of renal failure in diabetic nephropathy.

  title={Progression of renal failure in diabetic nephropathy.},
  author={Carmelita Marcantoni and Vittorio Ortalda and Antonio Lupo and Giuseppe Maschio},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  volume={13 Suppl 8},
The onset of renal damage in diabetes mellitus may be influenced by several factors which largely result from genetic predisposition, hereditary factors and the early appearance of microalbuminuria and/or systemic hypertension. Most of these factors are also implicated in the progression of nephropathy from microalbuminuria to overt proteinuria and to end-stage renal failure (ESRF). Over the last few years, the role of hyperglycaemia has emerged as critical in mediating the progressive renal… CONTINUE READING


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