Progression of pulmonary hyperinflation and trapped gas associated with genetic and environmental factors in children with cystic fibrosis

@article{Kraemer2006ProgressionOP,
  title={Progression of pulmonary hyperinflation and trapped gas associated with genetic and environmental factors in children with cystic fibrosis},
  author={Richard Kraemer and David N Baldwin and Roland A. Ammann and Urs Frey and Sabina Gallati},
  journal={Respiratory Research},
  year={2006},
  volume={7},
  pages={138 - 138}
}
BACKGROUND Functional deterioration in cystic fibrosis (CF) may be reflected by increasing bronchial obstruction and, as recently shown, by ventilation inhomogeneities. This study investigated which physiological factors (airway obstruction, ventilation inhomogeneities, pulmonary hyperinflation, development of trapped gas) best express the decline in lung function, and what role specific CFTR genotypes and different types of bronchial infection may have upon this process. METHODS Serial… CONTINUE READING

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